human MYCL1 shRNA silencing AAV

Name 
AAV-h-MYCL1-shRNA
Cat No 
shAAV-216141
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MYCL.

shAAV-216141
AAV-h-MYCL1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MYCL (v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bHLHe38; class E basic helix-loop-helix protein 38; LMYC; L-Myc; l-myc-1 proto-oncogene; MYCL1; myc-related gene from lung cancer; protein L-Myc; protein L-Myc-1; v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog; V-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived
Description (eCommerce)
MYCL1 binds DNA as a heterodimer with MAX [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P12524].
Gene ID
4610
Gene Name (eCommerce)
MYCL proto-oncogene, bHLH transcription factor
Gene Name (Vector)
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
Gene Symbol
MYCL
HGNC ID
HGNC:7555
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
621
ORF Size (bp)
621 bp
Protein Name (eCommerce)
Protein L-Myc
RefSeq ID
NM_005376
RefSeq Synonyms
NM_005376, NM_001033082, NM_001033081, BC011864,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
MYCL1 binds DNA as a heterodimer with MAX [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P12524].
UniGene ID
Hs.437922
UniProt ID (eCommerce)
P12524

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.