human MTMR15 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human FAN1.
shAAV-216015
AAV-h-MTMR15-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human FAN1 (FANCD2/FANCI-associated nuclease 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
coiled-coil domain-containing protein MTMR15; FANCD2/FANCI-associated nuclease 1; fanconi anemia associated nuclease 1; fanconi-associated nuclease 1; hFAN1; KIAA1018; KMIN; MTMR15; myotubularin-related protein 15
Description (eCommerce)
Myotubularin related protein 15 (MTMR15) bears a coiled-coil and Rad18-type zinc finger domain. The function of MTMR15 remains uncharacterized; but it may play a role in DNA repair.
Description (Vector)
FAN1 encodes a member of the myotubularin-related class 1 cysteine-based protein tyrosine phosphatases. The encoded protein may be catalytically inactive. Alternatively spliced transcript variants have been described.
Gene ID
22909
Gene Name (eCommerce)
FANCD2 and FANCI associated nuclease 1
Gene Name (Vector)
FANCD2/FANCI-associated nuclease 1
Gene Symbol
FAN1
HGNC ID
HGNC:29170
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1602
ORF Size (bp)
1602 bp
Protein Name (eCommerce)
Fanconi-associated nuclease 1
RefSeq ID
NM_014967
RefSeq Synonyms
NM_014967, NM_001146096, NM_001146095, NM_001146094, BC047882,
Research Areas
DNA Damage/Repair,Fanconi anemia,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Myotubularin related protein 15 (MTMR15) bears a coiled-coil and Rad18-type zinc finger domain. The function of MTMR15 remains uncharacterized; but it may play a role in DNA repair.
UniGene ID
Hs.584863
UniProt ID (eCommerce)
Q9Y2M0
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.