human MTAP shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MTAP.
shAAV-215970
AAV-h-MTAP-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MTAP (methylthioadenosine phosphorylase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BDMF; c86fus; DMSFH; DMSMFH; HEL-249; LGMBF; MSAP
Description (Vector)
MTAP encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
Gene ID
4507
Gene Name (Vector)
methylthioadenosine phosphorylase
Gene Symbol
MTAP
HGNC ID
HGNC:7413
ORF Size (aa)
729
RefSeq ID
NM_002451
RefSeq Synonyms
NM_002451, BC026106, BC018625, BC012316,
Species
human
UniGene ID
Hs.193268
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.