human MS4A12 shRNA silencing AAV

Name 
AAV-h-MS4A12-shRNA
Cat No 
shAAV-215887
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MS4A12.

shAAV-215887
AAV-h-MS4A12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MS4A12 (membrane spanning 4-domains A12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Ms4a10
Description (Vector)
MS4A12 is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
54860
Gene Name (Vector)
membrane spanning 4-domains A12
Gene Symbol
MS4A12
HGNC ID
HGNC:13370
ORF Size (aa)
804
RefSeq ID
NM_017716
RefSeq Synonyms
NM_017716, NM_001164470, BC029793,
Species
human
UniGene ID
Hs.272789

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.