human MRAS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MRAS.
shAAV-215746
AAV-h-MRAS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MRAS (muscle RAS oncogene homolog). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
M-RAs; R-RAS3; RRAS3
Description (Vector)
MRAS encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
22808
Gene Name (Vector)
muscle RAS oncogene homolog
Gene Symbol
MRAS
HGNC ID
HGNC:7227
ORF Size (aa)
627
RefSeq ID
NM_012219
RefSeq Synonyms
NM_012219, NM_001252093, NM_001252092, NM_001252091, NM_001252090, NM_001085049, BC156845, BC047690,
Species
human
UniGene ID
Hs.527021
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.