human MOCOS shRNA silencing AAV

Name 
AAV-h-MOCOS-shRNA
Cat No 
shAAV-215628
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MOCOS.

shAAV-215628
AAV-h-MOCOS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MOCOS (molybdenum cofactor sulfurase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HMCS; MCS; MoCo sulfurase; molybdenum cofactor sulfurase; Molybdenum cofactor sulfurtransferase; MOS
Description (eCommerce)
Molybdenum cofactor sulfurase (MOCOS) sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742] [taken from NCBI Entrez Gene (Gene ID: 55034)].
Description (Vector)
MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 (PubMed 11302742)).(supplied by OMIM, Feb 2010)
Gene ID
55034
Gene Name (eCommerce)
molybdenum cofactor sulfurase
Gene Name (Vector)
molybdenum cofactor sulfurase
Gene Symbol
MOCOS
HGNC ID
HGNC:18234
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2667
ORF Size (bp)
2667 bp
Protein Name (eCommerce)
Molybdenum cofactor sulfurase
RefSeq ID
NM_017947
RefSeq Synonyms
NM_017947, BC012079,
Research Areas
Metabolism/Metabolic Process
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
Molybdenum cofactor sulfurase (MOCOS) sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH; MIM 607633) and aldehyde oxidase (AOX1; MIM 602841), which is required for their enzymatic activities (Ichida et al., 2001 [PubMed 11302742] [taken from NCBI Entrez Gene (Gene ID: 55034)].
UniGene ID
Hs.405028
UniProt ID (eCommerce)
Q96EN8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.