human MMP16 shRNA silencing AAV

Name
AAV-h-MMP16-shRNA

Cat No
shAAV-215579

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MMP16.

shAAV-215579

AAV-h-MMP16-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MMP16 (matrix metallopeptidase 16). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

C8orf57; MMP-X2; MT-MMP2; MT-MMP3; MT3-MMP

Description (Vector)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

Gene ID

4325

Gene Name (Vector)

matrix metallopeptidase 16

Gene Symbol

MMP16

HGNC ID

HGNC:7162

ORF Size (aa)

1824

ORF Size (bp)

1824 bp

RefSeq ID

NM_005941

RefSeq Synonyms

NM_005941, BC075005, BC075004, BC069500,

Species

human

UniGene ID

Hs.546267

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.