human MMD shRNA silencing AAV

Name
AAV-h-MMD-shRNA

Cat No
shAAV-215556

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MMD.

shAAV-215556

AAV-h-MMD-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MMD (monocyte to macrophage differentiation associated). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MMA; MMD1; PAQR11

Description (Vector)

This protein is expressed by in vitro differentiated macrophages but not freshly isolated monocytes. Although sequence analysis identifies seven potential transmembrane domains, this protein has little homology to G-protein receptors and it has not been positively identified as a receptor. A suggested alternative function is that of an ion channel protein in maturing macrophages.

Gene ID

23531

Gene Name (Vector)

monocyte to macrophage differentiation associated

Gene Symbol

MMD

HGNC ID

HGNC:7153

ORF Size (aa)

717

RefSeq ID

NM_012329

RefSeq Synonyms

NM_012329, BC026324,

Species

human

UniGene ID

Hs.656753

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.