human MED21 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MED21.
shAAV-215253
AAV-h-MED21-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MED21 (mediator complex subunit 21). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
hSrb7; SRB7; SURB7
Description (Vector)
The Mediator is a multiprotein coactivator that is required by DNA-binding transcription factors for transcriptional activation of polymerase II (see MIM 180660)-transcribed genes. MED21 is a Mediator subunit predicted to reside in the middle module and appears to be a core subunit found in nearly all Mediator preparations (summary by Sato et al., 2004 (PubMed 15175163)).(supplied by OMIM, Nov 2010)
Gene ID
9412
Gene Name (Vector)
mediator complex subunit 21
Gene Symbol
MED21
HGNC ID
HGNC:11473
ORF Size (aa)
435
RefSeq ID
NM_004264
RefSeq Synonyms
NM_004264, NM_001271811, BC008380,
Species
human
UniGene ID
Hs.286145
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.