human MC2R shRNA silencing AAV

Name
AAV-h-MC2R-shRNA

Cat No
shAAV-215132

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MC2R.

shAAV-215132

AAV-h-MC2R-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MC2R (melanocortin 2 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ACTHR

Description (Vector)

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.

Gene ID

4158

Gene Name (Vector)

melanocortin 2 receptor

Gene Symbol

MC2R

HGNC ID

HGNC:6930

ORF Size (aa)

894

ORF Size (bp)

894 bp

RefSeq ID

NM_000529

RefSeq Synonyms

NM_001291911, NM_000529, BC104169, BC094710, BC069074,

Species

human

UniGene ID

Hs.248144

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.