human MARCO shRNA silencing AAV

Name
AAV-h-MARCO-shRNA

Cat No
shAAV-215034

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MARCO.

shAAV-215034

AAV-h-MARCO-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MARCO (macrophage receptor with collagenous structure). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SCARA2

Description (Vector)

MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Gene ID

8685

Gene Name (Vector)

macrophage receptor with collagenous structure

Gene Symbol

MARCO

HGNC ID

HGNC:6895

ORF Size (aa)

1563

ORF Size (bp)

1563 bp

RefSeq ID

NM_006770

RefSeq Synonyms

NM_006770, BC016004,

Species

human

UniGene ID

Hs.67726

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.