human MARCH3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human MARCH3.
shAAV-215019
AAV-h-MARCH3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human MARCH3 (membrane associated ring-CH-type finger 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MARCH-III; RNF173
Description (Vector)
MARCH3 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH3 appears to function in the endosomal recycling pathway (Fukuda et al., 2006 (PubMed 16428329)).(supplied by OMIM, Mar 2010)
Gene ID
115123
Gene Name (Vector)
membrane associated ring-CH-type finger 3
Gene Symbol
3-Mar
HGNC ID
HGNC:28728
ORF Size (aa)
762
RefSeq ID
NM_178450
RefSeq Synonyms
NM_178450, BC146964, BC146948, BC047569,
Species
human
UniGene ID
Hs.132441
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.