human MARCH10 shRNA silencing AAV

Name 
AAV-h-MARCH10-shRNA
Cat No 
shAAV-215014
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MARCH10.

shAAV-215014
AAV-h-MARCH10-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MARCH10 (membrane associated ring-CH-type finger 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MARCH-X; RNF190
Description (Vector)
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 (PubMed 17604280)).(supplied by OMIM, Apr 2010)
Gene ID
162333
Gene Name (Vector)
membrane associated ring-CH-type finger 10
Gene Symbol
10-Mar
HGNC ID
HGNC:26655
ORF Size (aa)
1974
ORF Size (bp)
1974 bp
RefSeq ID
NM_152598
RefSeq Synonyms
NM_152598, NM_001288780, NM_001288779, NM_001100875, BC035021,
Species
human
UniGene ID
Hs.665663

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.