human MAPKAPK5 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-215002
Availability:
4-5 weeks
Name:
AAV-h-MAPKAPK5-shRNA
This is an AAV expressing shRNA for silencing of Human MAPKAPK5.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MAPKAPK5
- Gene Name
- mitogen-activated protein kinase-activated protein kinase 5
- Gene ID
- 8550
- Gene Synonyms
- MAPKAP-K5; MK-5; MK5; PRAK
- ORF Size
- 1416 bp
- RefSeq#
- NM_003668
- Gene Description
- MAPKAPK5 is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.
- UniGene ID
- Hs.413901
- HGNC ID
- HGNC:6889
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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