human MAPK11 shRNA silencing AAV

Name 
AAV-h-MAPK11-shRNA
Cat No 
shAAV-214968
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAPK11.

shAAV-214968
AAV-h-MAPK11-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAPK11 (mitogen-activated protein kinase 11). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B
Description (Vector)
MAPK11 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
Gene ID
5600
Gene Name (Vector)
mitogen-activated protein kinase 11
Gene Symbol
MAPK11
HGNC ID
HGNC:6873
ORF Size (aa)
1095
ORF Size (bp)
1095 bp
RefSeq ID
NM_002751
RefSeq Synonyms
NM_002751, BC027933,
Species
human
UniGene ID
Hs.57732

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.