human MAP3K13 shRNA silencing AAV

Name 
AAV-h-MAP3K13-shRNA
Cat No 
shAAV-214927
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAP3K13.

shAAV-214927
AAV-h-MAP3K13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP3K13 (mitogen-activated protein kinase kinase kinase 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
LZK; MEKK13; MLK
Description (Vector)
MAP3K13 is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway.
Gene ID
9175
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 13
Gene Symbol
MAP3K13
HGNC ID
HGNC:6852
ORF Size (aa)
1971
ORF Size (bp)
1971 bp
RefSeq ID
NM_004721
RefSeq Synonyms
NM_004721, NM_001242317, NM_001242314, BC111726,
Species
human
UniGene ID
Hs.656069

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.