human MAL2 shRNA silencing AAV

Name 
AAV-h-MAL2-shRNA
Cat No 
shAAV-214861
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAL2.

shAAV-214861
AAV-h-MAL2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAL2 (mal, T-cell differentiation protein 2 (gene/pseudogene)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
98
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
MAL2 encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface.
Gene ID
114569
Gene Name (Vector)
mal, T-cell differentiation protein 2 (gene/pseudogene)
Gene Symbol
MAL2
HGNC ID
HGNC:13634
ORF Size (aa)
531
RefSeq ID
NM_052886
RefSeq Synonyms
NM_052886, BC012367,
Species
human
UniGene ID
Hs.201083

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.