human MAFG shRNA silencing AAV

Name
AAV-h-MAFG-shRNA

Cat No
shAAV-214797

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human MAFG.

shAAV-214797

AAV-h-MAFG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAFG (MAF bZIP transcription factor G). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

hMAF

Description (Vector)

Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 (PubMed 9166829)). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).(supplied by OMIM, Mar 2010)

Gene ID

4097

Gene Name (Vector)

MAF bZIP transcription factor G

Gene Symbol

MAFG

HGNC ID

HGNC:6781

ORF Size (aa)

489

RefSeq ID

NM_002359

RefSeq Synonyms

NM_032711, NM_002359, BC012327,

Species

human

UniGene ID

Hs.252229

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.