human MAEA shRNA silencing AAV

Name
AAV-h-MAEA-shRNA

Cat No
shAAV-214786

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MAEA.

shAAV-214786

AAV-h-MAEA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAEA (macrophage erythroblast attacher). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EMLP; EMP; GID9; HLC-10; PIG5

Description (Vector)

MAEA product mediates the attachment of erythroblasts to macrophages. This attachment promotes terminal maturation and enucleation of erythroblasts, presumably by suppressing apoptosis. This protein is an integral membrane protein with the N-terminus on the extracellular side and the C-terminus on the cytoplasmic side of the cell. Two immunologically related isoforms of erythroblast macrophage protein with apparent molecular weights of 33 kD and 36 kD were detected in macrophage membranes; this gene encodes the larger isoform. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Gene ID

10296

Gene Name (Vector)

macrophage erythroblast attacher

Gene Symbol

MAEA

HGNC ID

HGNC:13731

ORF Size (aa)

1191

ORF Size (bp)

1191 bp

RefSeq ID

NM_005882

RefSeq Synonyms

NM_005882, NM_001297433, NM_001297432, NM_001297431, NM_001297430, NM_001017405, BC001225,

Species

human

UniGene ID

Hs.139896

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.