human LRAT shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LRAT.
shAAV-214468
AAV-h-LRAT-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LRAT (lecithin retinol acyltransferase (phosphatidylcholine–retinol O-acyltransferase)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LCA14
Description (Vector)
LRAT is a microsomal enzyme that catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester, an essential reaction for the retinoid cycle in visual system and vitamin A status in liver. Mutations in this gene have been associated with early-onset severe retinal dystrophy.
Gene ID
9227
Gene Name (Vector)
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
Gene Symbol
LRAT
HGNC ID
HGNC:6685
ORF Size (aa)
693
RefSeq ID
NM_004744
RefSeq Synonyms
NM_004744, NM_001301645, BC031053,
Species
human
UniGene ID
Hs.658427
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.