human LPAR2 shRNA silencing AAV

Name
AAV-h-LPAR2-shRNA

Cat No
shAAV-214445

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LPAR2.

shAAV-214445

AAV-h-LPAR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LPAR2 (lysophosphatidic acid receptor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EDG-4; EDG4; LPA-2; LPA2

Description (Vector)

LPAR2 encodes a member of family I of the G protein-coupled receptors, as well as the EDG family of proteins. This protein functions as a lysophosphatidic acid (LPA) receptor and contributes to Ca2+ mobilization, a critical cellular response to LPA in cells, through association with Gi and Gq proteins. An alternative splice variant has been described but its full length sequence has not been determined.

Gene ID

9170

Gene Name (Vector)

lysophosphatidic acid receptor 2

Gene Symbol

LPAR2

HGNC ID

HGNC:3168

ORF Size (aa)

1056

ORF Size (bp)

1056 bp

RefSeq ID

NM_004720

RefSeq Synonyms

NM_004720, BC025695,

Species

human

UniGene ID

Hs.122575

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.