human LPAR1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-214443
Availability:
4-5 weeks
Name:
AAV-h-LPAR1-shRNA
This is an AAV expressing shRNA for silencing of Human LPAR1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- LPAR1
- Gene Name
- lysophosphatidic acid receptor 1
- Gene ID
- 1902
- Gene Synonyms
- edg-2; EDG2; Gpcr26; GPR26; LPA1; Mrec1.3; rec.1.3; vzg-1; VZG1
- ORF Size
- 1095 bp
- RefSeq#
- NM_057159
- Gene Description
- The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene
- UniGene ID
- Hs.126667
- HGNC ID
- HGNC:3166
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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