human PTDSS2 shRNA silencing AAV

Name
AAV-h-PTDSS2-shRNA

Cat No
shAAV-214136

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human PTDSS2.

shAAV-214136

AAV-h-PTDSS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human PTDSS2 (phosphatidylserine synthase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PSS2

Description (Vector)

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 (PubMed 11084049)).(supplied by OMIM, May 2009)

Gene ID

81490

Gene Name (Vector)

phosphatidylserine synthase 2

Gene Symbol

PTDSS2

HGNC ID

HGNC:15463

ORF Size (aa)

1464

ORF Size (bp)

1464 bp

RefSeq ID

NM_030783

RefSeq Synonyms

NM_030783, NM_001329548, NM_001329545, NM_001329544, BC001210,

Species

human

UniGene ID

Hs.12851

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.