human MAGT1 shRNA silencing AAV

Name
AAV-h-MAGT1-shRNA

Cat No
shAAV-214084

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MAGT1.

shAAV-214084

AAV-h-MAGT1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAGT1 (magnesium transporter 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

bA217H1.1; IAP; MRX95; OST3B; PRO0756; XMEN

Description (Vector)

MAGT1 encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). MAGT1 may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29.

Gene ID

84061

Gene Name (Vector)

magnesium transporter 1

Gene Symbol

MAGT1

HGNC ID

HGNC:28880

ORF Size (aa)

1008

ORF Size (bp)

1008 bp

RefSeq ID

NM_032121

RefSeq Synonyms

NM_032121, BC063037, BC060842, BC041014,

Species

human

UniGene ID

Hs.710189

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.