human LMO1 shRNA silencing AAV

Name
AAV-h-LMO1-shRNA

Cat No
shAAV-214033

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human LMO1.

shAAV-214033

AAV-h-LMO1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LMO1 (LIM domain only 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

RBTN1; RHOM1; TTG1

Description (Vector)

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

Gene ID

4004

Gene Name (Vector)

LIM domain only 1

Gene Symbol

LMO1

HGNC ID

HGNC:6641

ORF Size (aa)

414

RefSeq ID

NM_002315

RefSeq Synonyms

NM_002315, NM_001270428, BC096058, BC096057, BC096056, BC069793, BC069752, BC069673,

Species

human

UniGene ID

Hs.654426

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.