human LIAS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human LIAS.
shAAV-213914
AAV-h-LIAS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human LIAS (lipoic acid synthetase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HGCLAS; HUSSY-01; LAS; LIP1; LS; PDHLD
Description (Vector)
LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Gene ID
11019
Gene Name (Vector)
lipoic acid synthetase
Gene Symbol
LIAS
HGNC ID
HGNC:16429
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
RefSeq ID
NM_006859
RefSeq Synonyms
NM_194451, NM_006859, NM_001278592, NM_001278591, NM_001278590, BC062751, BC023635,
Species
human
UniGene ID
Hs.550502
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.