human LHX8 shRNA silencing AAV

Name
AAV-h-LHX8-shRNA

Cat No
shAAV-213912

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human LHX8.

shAAV-213912

AAV-h-LHX8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human LHX8 (LIM homeobox 8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

LHX7

Description (Vector)

LHX8 is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants.

Gene ID

431707

Gene Name (Vector)

LIM homeobox 8

Gene Symbol

LHX8

HGNC ID

HGNC:28838

ORF Size (aa)

1071

ORF Size (bp)

1071 bp

RefSeq ID

NM_001001933

RefSeq Synonyms

NM_001256114, NM_001001933, BC040321,

Species

human

UniGene ID

Hs.403934

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.