human KRT20 shRNA silencing AAV

Name 
AAV-h-KRT20-shRNA
Cat No 
shAAV-213396
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KRT20.

shAAV-213396
AAV-h-KRT20-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KRT20 (keratin 20). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD20; CK20; CK-20; cytokeratin 20; Cytokeratin-20; K20; keratin 20, type I; keratin, type I cytoskeletal 20; Keratin-20; KRT21; protein IT
Description (eCommerce)
Cytokeratin 20 is a member of the keratin family of intermediate filament proteins responsible for the structural integrity of epithelial cells. Cytokeratin 20 is a type I cytokeratin, acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. [taken from NCBI Entrez Gene (Gene ID: 54474)].
Description (Vector)
KRT20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Gene ID
54474
Gene Name (eCommerce)
keratin 20
Gene Name (Vector)
keratin 20
Gene Symbol
KRT20
HGNC ID
HGNC:20412
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1275
ORF Size (bp)
1275 bp
Protein Name (eCommerce)
Keratin, type I cytoskeletal 20
RefSeq ID
NM_019010
RefSeq Synonyms
NM_019010, BC031559,
Research Areas
Apoptosis,Cytoskeleton
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Cytokeratin 20 is a member of the keratin family of intermediate filament proteins responsible for the structural integrity of epithelial cells. Cytokeratin 20 is a type I cytokeratin, acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. [taken from NCBI Entrez Gene (Gene ID: 54474)].
UniGene ID
Hs.84905
UniProt ID (eCommerce)
P35900

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.