human KIN shRNA silencing AAV

Name
AAV-h-KIN-shRNA

Cat No
shAAV-213126

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human KIN.

shAAV-213126

AAV-h-KIN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KIN (Kin17 DNA and RNA binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

BTCD; KIN17; Rts2

Description (Vector)

KIN is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.

Gene ID

22944

Gene Name (Vector)

Kin17 DNA and RNA binding protein

Gene Symbol

KIN

HGNC ID

HGNC:6327

ORF Size (aa)

1182

ORF Size (bp)

1182 bp

RefSeq ID

NM_012311

RefSeq Synonyms

NM_012311, BC017309,

Species

human

UniGene ID

Hs.397918

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.