human KIAA1804 shRNA silencing AAV

Name
AAV-h-KIAA1804-shRNA

Cat No
shAAV-213043

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human MAP3K21.

shAAV-213043

AAV-h-KIAA1804-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP3K21 (mitogen-activated protein kinase kinase kinase 21). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dJ862P8.3; mitogen-activated protein kinase kinase kinase 21; mitogen-activated protein kinase kinase kinase MLK4; mixed lineage kinase 4; MLK4

Description (eCommerce)

Mixed lineage kinase 4 (MLK4) is a MAP kinase kinase kinase and may function in the activation of the JUN N-terminal pathway.

Gene ID

84451

Gene Name (eCommerce)

mitogen-activated protein kinase kinase kinase 21

Gene Name (Vector)

mitogen-activated protein kinase kinase kinase 21

Gene Symbol

MAP3K21

HGNC ID

HGNC:29798

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

3111

ORF Size (bp)

3111 bp

Protein Name (eCommerce)

Mitogen-activated protein kinase kinase kinase MLK4

RefSeq ID

NM_032435

RefSeq Synonyms

NM_032435, BC136649, BC136648,

Research Areas

Cell Biology,EPO Signaling,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,Phosphatase,Signal Transduction,Translational Control,VEGF Signaling

Research Areas (Faceted)

cell_biology,immunology,signal_transduction,transcription_translation

Species

human

Target Sentence

Mixed lineage kinase 4 (MLK4) is a MAP kinase kinase kinase and may function in the activation of the JUN N-terminal pathway.

UniGene ID

Hs.547779

UniProt ID (eCommerce)

Q5TCX8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.