human KDR shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human KDR.
shAAV-212862
AAV-h-KDR-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human KDR (kinase insert domain receptor). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD309; FLK1; VEGFR; VEGFR2
Description (Vector)
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
Gene ID
3791
Gene Name (Vector)
kinase insert domain receptor
Gene Symbol
KDR
HGNC ID
HGNC:6307
ORF Size (aa)
4071
ORF Size (bp)
4071 bp
RefSeq ID
NM_002253
RefSeq Synonyms
NM_002253, BC131822,
Species
human
UniGene ID
Hs.479756
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.