human KCTD12 shRNA silencing AAV

Name 
AAV-h-KCTD12-shRNA
Cat No 
shAAV-212799
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KCTD12.

shAAV-212799
AAV-h-KCTD12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCTD12 (potassium channel tetramerization domain containing 12). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
97
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BTB/POZ domain-containing protein KCTD12; C13orf2; PFET1; PFETIN; potassium channel tetramerisation domain containing 12; predominantly fetal expressed T1 domain; testicular tissue protein Li 100
Description (eCommerce)
Pfetin (predominantly fetal expressed T1 domain) was identified by subtractive hybridization and differential screening of human fetal cochlear cDNA clones. Pfetin contains a voltage-gated postassium (K+) channel tetramerization (T1) domain and has been found to interact as a tetramer with GABRB1 and GABRB2. Pfetin has also been identified as a prognostic biomarker of gastrointestinal stromal tumors.
Gene ID
115207
Gene Name (eCommerce)
potassium channel tetramerization domain containing 12
Gene Name (Vector)
potassium channel tetramerization domain containing 12
Gene Symbol
KCTD12
HGNC ID
HGNC:14678
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
978
ORF Size (bp)
978 bp
Protein Name (eCommerce)
BTB/POZ domain-containing protein KCTD12
RefSeq ID
NM_138444
RefSeq Synonyms
NM_138444, BC013764,
Research Areas
Neurobiology,Synapse,Transport
Research Areas (Faceted)
cell_biology,neurobiology
Species
human
Target Sentence
Pfetin (predominantly fetal expressed T1 domain) was identified by subtractive hybridization and differential screening of human fetal cochlear cDNA clones. Pfetin contains a voltage-gated postassium (K+) channel tetramerization (T1) domain and has been found to interact as a tetramer with GABRB1 and GABRB2. Pfetin has also been identified as a prognostic biomarker of gastrointestinal stromal tumors.
UniGene ID
Hs.644125
UniProt ID (eCommerce)
Q96CX2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.