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human KCNK3 shRNA silencing AAV

Name 
AAV-h-KCNK3-shRNA
Cat No 
shAAV-212746
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KCNK3.

shAAV-212746
AAV-h-KCNK3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNK3 (potassium two pore domain channel subfamily K member 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
K2p3.1; OAT1; PPH4; TASK; TASK-1; TBAK1
Description (Vector)
KCNK3 encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.
Gene ID
3777
Gene Name (Vector)
potassium two pore domain channel subfamily K member 3
Gene Symbol
KCNK3
HGNC ID
HGNC:6278
ORF Size (aa)
816
ORF Size (bp)
816 bp
RefSeq ID
NM_002246
RefSeq Synonyms
NM_002246, BC140701,
Species
human
UniGene ID
Hs.645288

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.