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human KCNIP3 shRNA silencing AAV

Name 
AAV-h-KCNIP3-shRNA
Cat No 
shAAV-212706
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human KCNIP3.

shAAV-212706
AAV-h-KCNIP3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNIP3 (potassium voltage-gated channel interacting protein 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CSEN; DREAM; KCHIP3
Description (Vector)
KCNIP3 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene ID
30818
Gene Name (Vector)
potassium voltage-gated channel interacting protein 3
Gene Symbol
KCNIP3
HGNC ID
HGNC:15523
ORF Size (aa)
771
ORF Size (bp)
771 bp
RefSeq ID
NM_013434
RefSeq Synonyms
NM_013434, NM_001034914, BC012850,
Species
human
UniGene ID
Hs.437376

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.