human KCNIP2 shRNA silencing AAV

Name
AAV-h-KCNIP2-shRNA

Cat No
shAAV-212705

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNIP2.

shAAV-212705

AAV-h-KCNIP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNIP2 (potassium voltage-gated channel interacting protein 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

KCHIP2

Description (Vector)

KCNIP2 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.

Gene ID

30819

Gene Name (Vector)

potassium voltage-gated channel interacting protein 2

Gene Symbol

KCNIP2

HGNC ID

HGNC:15522

ORF Size (aa)

759

ORF Size (bp)

759 bp

RefSeq ID

NM_014591

RefSeq Synonyms

NM_173197, NM_173195, NM_173194, NM_173193, NM_173192, NM_173191, NM_014591, BC034685,

Species

human

UniGene ID

Hs.97044

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.