human KCNG1 shRNA silencing AAV

Name
AAV-h-KCNG1-shRNA

Cat No
shAAV-212691

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human KCNG1.

shAAV-212691

AAV-h-KCNG1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KCNG1 (potassium voltage-gated channel modifier subfamily G member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

K13; KCNG; kH2; KV6.1

Description (Vector)

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This gene is abundantly expressed in skeletal muscle. Multiple alternatively spliced transcript variants have been found in normal and cancerous tissues.

Gene ID

3755

Gene Name (Vector)

potassium voltage-gated channel modifier subfamily G member 1

Gene Symbol

KCNG1

HGNC ID

HGNC:6248

ORF Size (aa)

1542

ORF Size (bp)

1542 bp

RefSeq ID

NM_002237

RefSeq Synonyms

NM_002237, BC046629, BC006367,

Species

human

UniGene ID

Hs.118695

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.