human KATNA1 shRNA silencing AAV

Name
AAV-h-KATNA1-shRNA

Cat No
shAAV-212633

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human KATNA1.

shAAV-212633

AAV-h-KATNA1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human KATNA1 (katanin catalytic subunit A1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene ID

11104

Gene Name (Vector)

katanin catalytic subunit A1

Gene Symbol

KATNA1

HGNC ID

HGNC:6216

ORF Size (aa)

936

ORF Size (bp)

936 bp

RefSeq ID

NM_007044

RefSeq Synonyms

NM_007044, NM_001204076, BC050428,

Species

human

UniGene ID

Hs.450175

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.