human ITPKC shRNA silencing AAV

Name
AAV-h-ITPKC-shRNA

Cat No
shAAV-212548

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human ITPKC.

shAAV-212548

AAV-h-ITPKC-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ITPKC (inositol-trisphosphate 3-kinase C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IP3-3KC; IP3KC

Description (Vector)

ITPKC encodes a member of the inositol 1,4,5-trisphosphate (Ins(1,4,5)P(3)) 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.

Gene ID

80271

Gene Name (Vector)

inositol-trisphosphate 3-kinase C

Gene Symbol

ITPKC

HGNC ID

HGNC:14897

ORF Size (aa)

2052

ORF Size (bp)

2052 bp

RefSeq ID

NM_025194

RefSeq Synonyms

NM_025194, BC060788,

Species

human

UniGene ID

Hs.515415

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.