Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human ITGB3BP shRNA silencing AAV

Name 
AAV-h-ITGB3BP-shRNA
Cat No 
shAAV-212510
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human ITGB3BP.

shAAV-212510
AAV-h-ITGB3BP-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human ITGB3BP (integrin subunit beta 3 binding protein). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CENP-R; CENPR; HSU37139; NRIF3; TAP20
Description (Vector)
ITGB3BP encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Gene ID
23421
Gene Name (Vector)
integrin subunit beta 3 binding protein
Gene Symbol
ITGB3BP
HGNC ID
HGNC:6157
ORF Size (aa)
534
RefSeq ID
NM_014288
RefSeq Synonyms
NM_014288, NM_001347148, NM_001347147, NM_001347145, NM_001206739, BC014385, BC009929,
Species
human
UniGene ID
Hs.166539

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.