human INTS12 shRNA silencing AAV

Name 
AAV-h-INTS12-shRNA
Cat No 
shAAV-212317
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human INTS12.

shAAV-212317
AAV-h-INTS12-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human INTS12 (integrator complex subunit 12). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
INT12; PHF22; SBBI22
Description (Vector)
INTS12 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 (PubMed 16239144)).(supplied by OMIM, Mar 2008)
Gene ID
57117
Gene Name (Vector)
integrator complex subunit 12
Gene Symbol
INTS12
HGNC ID
HGNC:25067
ORF Size (aa)
1389
ORF Size (bp)
1389 bp
RefSeq ID
NM_020395
RefSeq Synonyms
NM_020395, NM_001142471, BC014442,
Species
human
UniGene ID
Hs.480454

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.