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human IL31 shRNA silencing AAV

Name 
AAV-h-IL31-shRNA
Cat No 
shAAV-212183
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IL31.

shAAV-212183
AAV-h-IL31-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL31 (interleukin 31). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IL-31
Description (Vector)
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 (PubMed 15184896)).(supplied by OMIM, Mar 2008)
Gene ID
386653
Gene Name (Vector)
interleukin 31
Gene Symbol
IL31
HGNC ID
HGNC:19372
ORF Size (aa)
495
RefSeq ID
NM_001014336
RefSeq Synonyms
NM_001014336, BC133000, BC132998,
Species
human
UniGene ID
Hs.569071

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.