human IL2RG shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IL2RG.
shAAV-212176
AAV-h-IL2RG-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IL2RG (interleukin 2 receptor subunit gamma). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1
Description (Vector)
IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
Gene ID
3561
Gene Name (Vector)
interleukin 2 receptor subunit gamma
Gene Symbol
IL2RG
HGNC ID
HGNC:6010
ORF Size (aa)
1110
ORF Size (bp)
1110 bp
RefSeq ID
NM_000206
RefSeq Synonyms
NM_000206, BC014972,
Species
human
UniGene ID
Hs.84
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.