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human IL2RB shRNA silencing AAV

Name 
AAV-h-IL2RB-shRNA
Cat No 
shAAV-212175
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IL2RB.

shAAV-212175
AAV-h-IL2RB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IL2RB (interleukin 2 receptor subunit beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CD122; IL15RB; P70-75
Description (Vector)
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Gene ID
3560
Gene Name (Vector)
interleukin 2 receptor subunit beta
Gene Symbol
IL2RB
HGNC ID
HGNC:6009
ORF Size (aa)
1656
ORF Size (bp)
1656 bp
RefSeq ID
NM_000878
RefSeq Synonyms
NM_001346223, NM_001346222, NM_000878, BC025691,
Species
human
UniGene ID
Hs.474787

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.