human IGFALS shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human IGFALS.
shAAV-211923
AAV-h-IGFALS-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human IGFALS (insulin like growth factor binding protein acid labile subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
ACLSD; ALS
Description (Vector)
IGFALS is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
3483
Gene Name (Vector)
insulin like growth factor binding protein acid labile subunit
Gene Symbol
IGFALS
HGNC ID
HGNC:5468
ORF Size (aa)
1818
ORF Size (bp)
1818 bp
RefSeq ID
NM_004970
RefSeq Synonyms
NM_004970, NM_001146006, BC025681,
Species
human
UniGene ID
Hs.839
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.