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human IFNAR2 shRNA silencing AAV

Name 
AAV-h-IFNAR2-shRNA
Cat No 
shAAV-211867
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human IFNAR2.

shAAV-211867
AAV-h-IFNAR2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human IFNAR2 (interferon alpha and beta receptor subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
IFN-alpha-REC; IFN-R; IFNABR; IFNARB; IMD45
Description (Vector)
IFNAR2 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.
Gene ID
3455
Gene Name (Vector)
interferon alpha and beta receptor subunit 2
Gene Symbol
IFNAR2
HGNC ID
HGNC:5433
ORF Size (aa)
996
ORF Size (bp)
996 bp
RefSeq ID
NM_000874
RefSeq Synonyms
NM_207585, NM_207584, NM_001289128, NM_001289126, NM_001289125, NM_000874, BC002793,
Species
human
UniGene ID
Hs.708195

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.