human HRG shRNA silencing AAV

Name
AAV-h-HRG-shRNA

Cat No
shAAV-211521

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HRG.

shAAV-211521

AAV-h-HRG-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HRG (histidine rich glycoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HPRG; HRGP; THPH11

Description (Vector)

This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

Gene ID

3273

Gene Name (Vector)

histidine rich glycoprotein

Gene Symbol

HRG

HGNC ID

HGNC:5181

ORF Size (aa)

1578

ORF Size (bp)

1578 bp

RefSeq ID

NM_000412

RefSeq Synonyms

NM_000412, BC150591, BC069574,

Species

human

UniGene ID

Hs.1498

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.