human HPSE shRNA silencing AAV

Name
AAV-h-HPSE-shRNA

Cat No
shAAV-211508

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HPSE.

shAAV-211508

AAV-h-HPSE-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HPSE (heparanase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

HPA; HPA1; HPR1; HPSE1; HSE1

Description (Vector)

Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Gene ID

10855

Gene Name (Vector)

heparanase

Gene Symbol

HPSE

HGNC ID

HGNC:5164

ORF Size (aa)

1632

ORF Size (bp)

1632 bp

RefSeq ID

NM_006665

RefSeq Synonyms

NM_006665, NM_001199830, NM_001166498, NM_001098540, BC051321,

Species

human

UniGene ID

Hs.44227

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.