human HOXB13 shRNA silencing AAV

Name
AAV-h-HOXB13-shRNA

Cat No
shAAV-211450

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human HOXB13.

shAAV-211450

AAV-h-HOXB13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HOXB13 (homeobox B13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PSGD

Description (Vector)

HOXB13 encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. HOXB13 has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. HOXB13 and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.

Gene ID

10481

Gene Name (Vector)

homeobox B13

Gene Symbol

HOXB13

HGNC ID

HGNC:5112

ORF Size (aa)

855

ORF Size (bp)

855 bp

RefSeq ID

NM_006361

RefSeq Synonyms

NM_006361, BC070233, BC007092,

Species

human

UniGene ID

Hs.66731

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.