human HK1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-211203
Availability:
4-5 weeks
Name:
AAV-h-HK1-shRNA
This is an AAV expressing shRNA for silencing of Human HK1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HK1
- Gene Name
- hexokinase 1
- Gene ID
- 3098
- Gene Synonyms
- hexokinase; HK; HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1
- ORF Size
- 2754 bp
- RefSeq#
- NM_033498
- Gene Description
- Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
- UniGene ID
- Hs.370365
- HGNC ID
- HGNC:4922
Related Products
Product | Cat No. |
---|---|
AAV-h-HK1 | AAV-211203 |
AAV-m-HK1 | AAV-261425 |
Ad-h-HK1 | ADV-211203 |
Ad-m-HK1 | ADV-261425 |
AAV-m-HK1-shRNA | shAAV-261425 |
Ad-h-HK1-shRNA | shADV-211203 |
Ad-m-HK1-shRNA | shADV-261425 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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