human HIST1H2AH shRNA silencing AAV

Name
AAV-h-HIST1H2AH-shRNA

Cat No
shAAV-211075

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human HIST1H2AH.

shAAV-211075

AAV-h-HIST1H2AH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human HIST1H2AH (histone cluster 1 H2A family member h). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

dJ86C11.1; H2A/S; H2AFALii; H2AH

Description (Vector)

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33.

Gene ID

85235

Gene Name (Vector)

histone cluster 1 H2A family member h

Gene Symbol

HIST1H2AH

HGNC ID

HGNC:13671

ORF Size (aa)

387

RefSeq ID

NM_080596

RefSeq Synonyms

NM_080596, BC148293, BC141469, BC134366, BC093851, BC093849,

Species

human

UniGene ID

Hs.352225

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.